Have researchers at Yale University discovered the technology to overcome death by restoring the function of porcine cells and organs after death?
Death is normally inevitable. A few minutes after the last beat of the heart, a cascade of biochemical events triggers the destruction of cells and organs in the body. A team of scientists from Yale University in the United States, however, discovered that this massive and permanent cell failure does not have to happen so quickly. She succeeded in counter this death-induced mass destruction of the subject, a pig.
OrganEx, the technology against death
Yale’s medical research arm has developed technology that delivers a special fluid that protects the cells of organs and tissuess. The researchers succeeded in restoring blood circulation and other cellular functions in pigs one hour after death.
David Andrijevic said that cell death with the death of its owner is not inevitable. He is an associate neuroscientist at Yale and also a co-lead author of the study. This researcher claims that he is possible to intervene, stop the process and restore some of the cellular functions.
This technology called OrganEx is based on BrainEx, another 2019 technology restoring the brain cell functions of a dead pig. OrganEx is a modified version of BrainEx. The researchers were able to detect signs of preservation of certain motor functions. They also demonstrated a restoration of certain cellular and tissue functions. However, they observed no organized electrical activity indicative of consciousness.
OrganEx, its litters
These results show the possibility of prolong the health of human organs to optimize their availability for organ transplants. The technology could also allow the preservation of organs and tissues damaged by ischemia even if the subject is not yet dead. This would be the case in particular during possible heart attacks or cerebral vascular accidents.
OrganEx has indeed many potential applications according to Stephen Latham, the director of Yale Interdisciplinary Center for Bioethics. Research is ongoing, however, and more discoveries may yet follow. The US Department of Health and Human Services, National Institutes of Health funded this research.